Navigation

Recent Publications

More...

Home

Unveiling the characteristics of the emerging Staphylococcus lugdunensis clone by genomics analysis

cjliu - Posted on 31 May 2017

Project Description: 

S. lugdunensis is a pathogen that can cause fatal infections in the clinical settings. This project aimed to investigate the antibiotic resistances, the evolution and transmission histories of this clone through whole genome sequencing (WGS) analysis.

Researcher name: 
LIU Chunjiao, Melissa
Researcher position: 
PhD(c)
Researcher department: 
Department of Microbiology
Researcher email: 
cjliu@hku.hk
Research Project Details
Project Duration: 
09/2015 to 08/2019
Project Significance: 
This emerging clone benefited from surviving the current antibiotic treatments, e.g., oxacillin, mupirocin, and gentamicin. This clone emerged from another sequence type decades ago and evolved continuously within this clone. The project is supported by the Health and Medical Research Fund.
Results Achieved: 
1. Ho, P. L., Liu, M. C. J., Chow, K. H., Tse, C. W. S., Lo, W. U., Mak, S. K., & Lo, W. K. (2016). Emergence of ileS2-carrying, multidrug-resistant plasmids in Staphylococcus lugdunensis. Antimicrobial Agents and Chemotherapy, 60(10), 6411-6414. 2. Liu, M. C. J. (2016). NZMS-NZSBMB 2016: Mupirocin Resistance among Staphylococcus lugdunensis between two nephrology centers in Hong Kong. (Poster, NZMS-NZSBMB 2016, Christchurch, New Zealand). 3. Liu, M. C. J. (2016). 21st HKU PGS: Mupirocin Resistance among Staphylococcus lugdunensis in Hong Kong. (Poster, 21st HKU PGS, Hong Kong, China).